Journal: Methods (San Diego, Calif.)
Article Title: Quantifying Transcription Factor Binding Dynamics at the Single-molecule Level in Live Cells
doi: 10.1016/j.ymeth.2017.03.014
Figure Lengend Snippet: (A) Performance based on the Jaccard Index of TrackRecord compared to the various methods described in, and using the simulated, medium density receptor data from Chenouard, et al [43] at several signal-to-noise values. (B) Extracted residence times from the same data as shown in (A) with a signal-to-noise value of 4 for Method 11 from Chenouard, et al [43], and TrackRecord. Although Method 11 performs better at tracking than TrackRecord based on the Jaccard Index in this scenario, TrackRecord is able to capture a wider range of residence time distributions than Method 11.
Article Snippet: 3.3 Data analysis Tracking was performed with the custom software TrackRecord [ 42 ] in MATLAB (The MathWorks, Inc., Natick, MA).
Techniques: